NLRP3 inflammasome activation in cigarette smoke priming for Pseudomonas aeruginosa-induced acute lung injury

NLRP3 inflammasome activation in cigarette smoke priming for Pseudomonas aeruginosa-induced acute lung injury

It is increasingly recognized that cigarette smoke (CS) exposure increases the incidence and severity of acute respiratory distress syndrome (ARDS) in critical ill humans and animals. However, the mechanism(s) is not well understood. This study aims to investigate mechanism underlying the priming ef...

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Bibliographic Details
Main Authors: Alexis White, Zhengke Wang, Xing Wang, Michelle King, Cynthia Guo, Chris Mantsounga, Alfred Ayala, Alan R. Morrison, Gaurav Choudhary, Frank Sellke, Eboni Chambers, Lorraine B. Ware, Sharon Rounds, Qing Lu
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:Redox Biology
Subjects:
Acute lung injury
Acute respiratory distress syndrome
Mitochondria
Inflammasome
Alveolar macrophages
Mitophagy
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231722002397

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http://www.sciencedirect.com/science/article/pii/S2213231722002397

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