HIV-1 with gag processing defects activates cGAS sensing
Abstract Background Detection of viruses by host pattern recognition receptors induces the expression of type I interferon (IFN) and IFN-stimulated genes (ISGs), which suppress viral replication. Numerous studies have described HIV-1 as a poor activator of innate immunity in vitro. The exact role th...
| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | English |
| Publicado em: |
BMC
2024-05-01
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| coleção: | Retrovirology |
| Assuntos: | |
| Acesso em linha: | https://doi.org/10.1186/s12977-024-00643-0 |