Dose-related shifts in proteome and function of extracellular vesicles secreted by fetal neural stem cells following chronic alcohol exposure

Dose-related shifts in proteome and function of extracellular vesicles secreted by fetal neural stem cells following chronic alcohol exposure

Accumulating evidence indicates that extracellular vesicles (EVs) mediate endocrine functions and also pathogenic effects of neurodevelopmental perturbagens like ethanol. We performed mass-spectrometry on EVs secreted by fetal murine cerebral cortical neural stem cells (NSCs), cultured ex-vivo as se...

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Bibliographic Details
Main Authors: Dae D. Chung, Marisa R. Pinson, Amanda H. Mahnke, Nihal A. Salem, Khang T. Le, Elizabeth A. Payne, Tenley E. Lehman, Susan T. Weintraub, Rajesh C. Miranda
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:Heliyon
Subjects:
Prenatal alcohol exposure
Fetal alcohol spectrum disorder
Extracellular vesicle
Neural stem cell
Developmental
Proteome
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844022026366

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http://www.sciencedirect.com/science/article/pii/S2405844022026366

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