In Vitro Activity of Monofunctional Pt-II Complex Based on 8-Aminoquinoline against Human Glioblastoma

In Vitro Activity of Monofunctional Pt-II Complex Based on 8-Aminoquinoline against Human Glioblastoma

A new cationic Pt(II) complex bearing 8-aminoquinoline as chelating ligand (called Pt-8AQ) was evaluated against two human carcinomas, one mesothelioma, and three glioblastoma cell lines. The in vitro comparison to the clinically approved CisPt showed a minor activity of Pt-8AQ against carcinoma and...

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Bibliographic Details
Main Authors: Valentina Coccè, Isabella Rimoldi, Giorgio Facchetti, Emilio Ciusani, Giulio Alessandri, Lucia Signorini, Francesca Sisto, Aldo Giannì, Francesca Paino, Augusto Pessina
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Pharmaceutics
Subjects:
mesenchymal stromal cells
glioblastoma
monofunctional Pt-II complex
cisplatin
Online Access:https://www.mdpi.com/1999-4923/13/12/2101

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https://www.mdpi.com/1999-4923/13/12/2101

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