Combination of Panax ginseng C. A. Mey and Febuxostat Boasted Cardioprotective Effects Against Doxorubicin-Induced Acute Cardiotoxicity in Rats

Combination of Panax ginseng C. A. Mey and Febuxostat Boasted Cardioprotective Effects Against Doxorubicin-Induced Acute Cardiotoxicity in Rats

Doxorubicin (DOX) is an anticancer agent for treating solid and soft tissue malignancies. However, the clinical use of DOX is restricted by cumulative, dose-dependent cardiotoxicity. Therefore, the present study aimed to assess the cardioprotective effects of P. ginseng C. A. Mey, febuxostat, and th...

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Bibliographic Details
Main Authors: Hayder M. Al-Kuraishy, Hany A. Al-Hussaniy, Ali I. Al-Gareeb, Walaa A. Negm, Aya H. El-Kadem, Gaber El-Saber Batiha, Nermeen N. Welson, Gomaa Mostafa-Hedeab, Ahmed H Qasem, Carlos Adam Conte-Junior
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Pharmacology
Subjects:
doxorubicin
ginseng
febuxostat
cardiac tropinin
BNP
TNF-α
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.905828/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.905828/full

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