Cell Cycle Regulation by Alternative Polyadenylation of CCND1
Abstract Global shortening of 3′UTRs by alternative polyadenylation (APA) has been observed in cancer cells. However, the role of APA in cancer remains unknown. CCND1 is a proto-oncogene that regulates progression through the G1-S phase of the cell cycle; moreover, it has been observed to be switchi...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2018-05-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-018-25141-0 |