Skin damage induced by zinc oxide nanoparticles combined with UVB is mediated by activating cell pyroptosis via the NLRP3 inflammasome–autophagy–exosomal pathway

Skin damage induced by zinc oxide nanoparticles combined with UVB is mediated by activating cell pyroptosis via the NLRP3 inflammasome–autophagy–exosomal pathway

Abstract Background Zinc oxide nanoparticles (ZnONPs) are widely used nanomaterial in personal cosmetics, such as skin creams and sunscreens, due to their whitening properties and strong UV light absorption. However, the safety issues and the hazards of ZnONPs, which can be taken up by the skin and...

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Bibliographic Details
Main Authors: Yu-Ying Chen, Yu-Hsuan Lee, Bour-Jr Wang, Rong-Jane Chen, Ying-Jan Wang
Format: Article
Language:English
Published: BMC 2022-01-01
Series:Particle and Fibre Toxicology
Subjects:
Zinc oxide nanoparticles
NLRP3 inflammasomes
Pyroptosis
Autophagy
Exosomes
Online Access:https://doi.org/10.1186/s12989-021-00443-w

Internet

https://doi.org/10.1186/s12989-021-00443-w

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