Peripheral Upregulation of Parkinson’s Disease-Associated Genes Encoding α-Synuclein, β-Glucocerebrosidase, and Ceramide Glucosyltransferase in Major Depression

Peripheral Upregulation of Parkinson’s Disease-Associated Genes Encoding α-Synuclein, β-Glucocerebrosidase, and Ceramide Glucosyltransferase in Major Depression

Due to the high comorbidity of Parkinson’s disease (PD) with major depressive disorder (MDD) and the involvement of sphingolipids in both conditions, we investigated the peripheral expression levels of three primarily PD-associated genes: α-synuclein (<i>SNCA</i>), lysosomal enzyme β-glu...

Full description

Bibliographic Details
Main Authors: Razvan-Marius Brazdis, Claudia von Zimmermann, Bernd Lenz, Johannes Kornhuber, Christiane Mühle
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:International Journal of Molecular Sciences
Subjects:
affective disorder
anxiety
biomarker
<i>GBA1</i>
gene expression
major depressive disorder
Online Access:https://www.mdpi.com/1422-0067/25/6/3219

Internet

https://www.mdpi.com/1422-0067/25/6/3219

Similar Items