SHH and Notch regulate SOX9+ progenitors to govern arcuate POMC neurogenesis

Pro-opiomelanocortin (POMC)-expressing neurons in the hypothalamic arcuate nucleus (ARC) play key roles in feeding and energy homoeostasis, hence their development is of great research interest. As the process of neurogenesis is accompanied by changes in adhesion, polarity, and migration that resemb...

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Bibliographic Details
Main Authors: Elsie Place, Elizabeth Manning, Dong Won Kim, Arisa Kinjo, Go Nakamura, Kyoji Ohyama
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2022.855288/full