T-cell receptor variable region usage in Chagas disease: A systematic review of experimental and human studies

T cells recognize their ligand, the peptide major histocompatibility complex (MHC), via the T-cell receptor (TCR), which is composed of covalently linked α and β or γ and δ chains. This recognition is critical for T-cell ontogeny and controls the selection, activation, and function of T lymphocytes....

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Bibliographic Details
Main Authors: Thaiany Goulart de Souza-Silva, Kenneth J. Gollob, Walderez O. Dutra
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-09-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9477334/?tool=EBI