T-cell receptor variable region usage in Chagas disease: A systematic review of experimental and human studies
T cells recognize their ligand, the peptide major histocompatibility complex (MHC), via the T-cell receptor (TCR), which is composed of covalently linked α and β or γ and δ chains. This recognition is critical for T-cell ontogeny and controls the selection, activation, and function of T lymphocytes....
Main Authors: | Thaiany Goulart de Souza-Silva, Kenneth J. Gollob, Walderez O. Dutra |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2022-09-01
|
Series: | PLoS Neglected Tropical Diseases |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9477334/?tool=EBI |
Similar Items
-
Cytokine Networks as Targets for Preventing and Controlling Chagas Heart Disease
by: Carolina Cattoni Koh, et al.
Published: (2023-01-01) -
Acute chagas disease: new global challenges for an old neglected disease.
by: Daniela V Andrade, et al.
Published: (2014-01-01) -
Correlation of blood-based immune molecules with cardiac gene expression profiles reveals insights into Chagas cardiomyopathy pathogenesis
by: Thaiany G. Souza-Silva, et al.
Published: (2024-02-01) -
Cellular and genetic mechanisms involved in the generation of protective and pathogenic immune responses in human Chagas disease
by: Walderez Ornelas Dutra, et al.
Published: (2009-07-01) -
Balancing the functions of DNA extracellular traps in intracellular parasite infections: implications for host defense, disease pathology and therapy
by: Carolina Cattoni Koh, et al.
Published: (2023-07-01)