Revolving hexameric ATPases as asymmetric motors to translocate double-stranded DNA genome along one strand

Summary: DsDNA translocation through nanoscale pores is generally accomplished by ATPase biomotors. The discovery of the revolving dsDNA translocation mechanism, as opposed to rotation, in bacteriophage phi29 elucidated how ATPase motors move dsDNA. Revolution-driven, hexameric dsDNA motors have bee...

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Bibliographic Details
Main Authors: Margaret Bohmer, Abhjeet S. Bhullar, Tao Weitao, Long Zhang, Jing-Huei Lee, Peixuan Guo
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223009999