Overexpressing 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGR) in the lactococcal mevalonate pathway for heterologous plant sesquiterpene production.

Isoprenoids are a large and diverse group of metabolites with interesting properties such as flavour, fragrance and therapeutic properties. They are produced via two pathways, the mevalonate pathway or the 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway. While plants are the richest source of isop...

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Bibliographic Details
Main Authors: Adelene Ai-Lian Song, Janna Ong Abdullah, Mohd Puad Abdullah, Norazizah Shafee, Roohaida Othman, Ee-Fun Tan, Normah Mohd Noor, Abdul Rahim Raha
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3530464?pdf=render