Effects of Aged Garlic Extract on Cholinergic, Glutamatergic and GABAergic Systems with Regard to Cognitive Impairment in Aβ-Induced Rats

Effects of Aged Garlic Extract on Cholinergic, Glutamatergic and GABAergic Systems with Regard to Cognitive Impairment in Aβ-Induced Rats

Alzheimer’s disease (AD) has been linked to the degeneration of central cholinergic and glutamatergic transmission, which correlates with progressive memory loss and the accumulation of amyloid-β (Aβ). It has been claimed that aged garlic extract (AGE) has a beneficial effect in preventing neurodege...

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Bibliographic Details
Main Authors: Piyaporn Thorajak, Wanassanun Pannangrong, Jariya Umka Welbat, Wunnee Chaijaroonkhanarak, Kittisak Sripanidkulchai, Bungorn Sripanidkulchai
Format: Article
Language:English
Published: MDPI AG 2017-07-01
Series:Nutrients
Subjects:
aged garlic extract
Alzheimer’s disease
amyloid-β
cholinergic neurons
glutamate decarboxylase
radial arm maze
vesicular glutamate transporters
Online Access:https://www.mdpi.com/2072-6643/9/7/686

Internet

https://www.mdpi.com/2072-6643/9/7/686

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