In Vitro Nephrotoxicity and Permeation of Vancomycin Hydrochloride Loaded Liposomes

In Vitro Nephrotoxicity and Permeation of Vancomycin Hydrochloride Loaded Liposomes

Drugs can be toxic to the fetus depending on the amount that permeates across the maternal–fetal barrier. One way to limit the amount which penetrates this barrier is to increase the molecular size of the drug. In this study, we have achieved this by encapsulating our model antibiotic (vancomycin hy...

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Bibliographic Details
Main Authors: Nicole Papp, Jeffin Panicker, John Rubino, Gwendolyn Pais, Alexander Czechowicz, Walter C. Prozialeck, Brooke Griffin, Volkmar Weissig, Marc Scheetz, Medha D. Joshi
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Pharmaceutics
Subjects:
vancomycin hydrochloride
in vitro toxicity
nephrotoxicity
placental permeation
Online Access:https://www.mdpi.com/1999-4923/14/6/1153

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https://www.mdpi.com/1999-4923/14/6/1153

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