Replication protein A plays multifaceted roles complementary to specialized helicases in processing G-quadruplex DNA

Replication protein A plays multifaceted roles complementary to specialized helicases in processing G-quadruplex DNA

Summary: G-quadruplexes (G4s) are non-canonical DNA structures with critical roles in DNA metabolisms. To resolve those structures that can cause replication fork stalling and genomic instability, single-stranded DNA-binding proteins and helicases are required. Here, we characterized the interplay b...

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Bibliographic Details
Main Authors: Yi-Ran Wang, Ting-Ting Guo, Ya-Ting Zheng, Chang-Wei Lai, Bo Sun, Xu-Guang Xi, Xi-Miao Hou
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:iScience
Subjects:
Molecular structure
Molecular biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221004612

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http://www.sciencedirect.com/science/article/pii/S2589004221004612

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