IGFBPs were associated with stemness, inflammation, extracellular matrix remodeling and poor prognosis of low-grade glioma

IGFBPs were associated with stemness, inflammation, extracellular matrix remodeling and poor prognosis of low-grade glioma

BackgroundThe IGFBP family of insulin-like growth factor binding proteins has important biological functions in the organism. However, the role of the IGFBP family in low-grade glioma (LGG) has not been fully explored.MethodsWe validated the clinical value of the IGFBP family using RNA-seq and clini...

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Bibliographic Details
Main Authors: Zhihui Liu, Hang Ji, Wenchao Fu, Shuai Ma, Hongtao Zhao, Fang Wang, Jiawei Dong, Xiuwei Yan, Jiheng Zhang, Nan Wang, Jiasheng Wu, Shaoshan Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Endocrinology
Subjects:
extracellular matrix
metabolism
stemness
inflammation
insulin-like growth factor binding protein (IGFBP)
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.943300/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2022.943300/full

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