CD70 and PD‐L1 (CD274) co‐expression predicts poor clinical outcomes in patients with pleural mesothelioma

CD70 and PD‐L1 (CD274) co‐expression predicts poor clinical outcomes in patients with pleural mesothelioma

Abstract Diffuse pleural mesothelioma (PM) is a highly aggressive tumour typically associated with short survival. Recently, the effectiveness of first‐line immune checkpoint inhibitors in patients with unresectable PM was reported. CD70–CD27 signalling plays a co‐stimulatory role in promoting T cel...

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Bibliographic Details
Main Authors: Shingo Inaguma, Akane Ueki, Jerzy Lasota, Masayuki Komura, Asraful Nahar Sheema, Piotr Czapiewski, Renata Langfort, Janusz Rys, Joanna Szpor, Piotr Waloszczyk, Krzysztof Okoń, Wojciech Biernat, David S Schrump, Raffit Hassan, Markku Miettinen, Satoru Takahashi
Format: Article
Language:English
Published: Wiley 2023-05-01
Series:The Journal of Pathology: Clinical Research
Subjects:
pleural mesothelioma
immunohistochemistry
CD70
PD‐L1 (CD274)
migration
invasion
Online Access:https://doi.org/10.1002/cjp2.310

Internet

https://doi.org/10.1002/cjp2.310

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