Phospholipase C-β1 hypofunction in the pathogenesis of schizophrenia

Phospholipase C-β1 hypofunction in the pathogenesis of schizophrenia

Schizophrenia is a mental disorder that is characterized by various abnormal symptoms. Previous studies indicate decreased expression of Phospholipase C-β1 (PLC-β1) in the brains of patients with schizophrenia. PLC-β1-null (PLC-β1-/-) mice exhibit multiple endophenotypes of schizophrenia. Furthermor...

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Bibliographic Details
Main Authors: Seong-Wook eKim, Taesup eCho, Sukchan eLee
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-11-01
Series:Frontiers in Psychiatry
Subjects:
Schizophrenia
DLPFC
mPFC
PLC-β1
Schizophrenia endophenotypes
Online Access:http://journal.frontiersin.org/Journal/10.3389/fpsyt.2015.00159/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fpsyt.2015.00159/full

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