Effect of pharmacogenetics on plasma lumefantrine pharmacokinetics and malaria treatment outcome in pregnant women

Abstract Background Pregnancy has considerable effects on the pharmacokinetic properties of drugs used to treat uncomplicated Plasmodium falciparum malaria. The role of pharmacogenetic variation on anti-malarial drug disposition and efficacy during pregnancy is not well investigated. The study aimed...

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Bibliographic Details
Main Authors: Ritah F. Mutagonda, Appolinary A. R. Kamuhabwa, Omary M. S. Minzi, Siriel N. Massawe, Muhammad Asghar, Manijeh V. Homann, Anna Färnert, Eleni Aklillu
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Malaria Journal
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12936-017-1914-9