β‐Catenin activity induces an RNA biosynthesis program promoting therapy resistance in T‐cell acute lymphoblastic leukemia

β‐Catenin activity induces an RNA biosynthesis program promoting therapy resistance in T‐cell acute lymphoblastic leukemia

Abstract Understanding the molecular mechanisms that contribute to the appearance of chemotherapy resistant cell populations is necessary to improve cancer treatment. We have now investigated the role of β‐catenin/CTNNB1 in the evolution of T‐cell Acute Lymphoblastic Leukemia (T‐ALL) patients and it...

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Bibliographic Details
Main Authors: Violeta García‐Hernández, David Arambilet, Yolanda Guillén, Teresa Lobo‐Jarne, María Maqueda, Christos Gekas, Jessica González, Arnau Iglesias, Nerea Vega‐García, Inés Sentís, Juan L Trincado, Ian Márquez‐López, Holger Heyn, Mireia Camós, Lluis Espinosa, Anna Bigas
Format: Article
Language:English
Published: Springer Nature 2023-01-01
Series:EMBO Molecular Medicine
Subjects:
chemotherapy resistance
Kaiso
RNA processing
T‐ALL
β‐catenin
Online Access:https://doi.org/10.15252/emmm.202216554

Internet

https://doi.org/10.15252/emmm.202216554

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