A stepwise-targeting strategy for the treatment of cerebral ischemic stroke

A stepwise-targeting strategy for the treatment of cerebral ischemic stroke

Abstract Background Effective amelioration of neuronal damages in the case of cerebral ischemic stroke (CIS) is essential for the protection of brain tissues and their functional recovery. However, most drugs can not penetrate the blood–brain barrier (BBB), resulting in the poor therapeutic outcomes...

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Bibliographic Details
Main Authors: Jingbo Hu, Xueying Tan, Dongwei Wang, Yixuan Li, Hongze Liang, Jiejun Peng, Fengyan Li, Quan Zhou, Peiwu Geng, Shuanghu Wang, Yue Yu, Jin Liu
Format: Article
Language:English
Published: BMC 2021-11-01
Series:Journal of Nanobiotechnology
Subjects:
Cerebral ischemic stroke
Stepwise-targeting delivery
Oxidative stress
Melatonin
Micelles
Online Access:https://doi.org/10.1186/s12951-021-01118-6

Internet

https://doi.org/10.1186/s12951-021-01118-6

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