Novel Klebsiella pneumoniae K23-Specific Bacteriophages From Different Families: Similarity of Depolymerases and Their Therapeutic Potential

Novel Klebsiella pneumoniae K23-Specific Bacteriophages From Different Families: Similarity of Depolymerases and Their Therapeutic Potential

Antibiotic resistance is a major public health concern in many countries worldwide. The rapid spread of multidrug-resistant (MDR) bacteria is the main driving force for the development of novel non-antibiotic antimicrobials as a therapeutic alternative. Here, we isolated and characterized three viru...

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Main Authors: Roman B. Gorodnichev, Nikolay V. Volozhantsev, Valentina M. Krasilnikova, Ivan N. Bodoev, Maria A. Kornienko, Nikita S. Kuptsov, Anastasia V. Popova, Galina I. Makarenko, Alexander I. Manolov, Pavel V. Slukin, Dmitry A. Bespiatykh, Vladimir V. Verevkin, Egor A. Denisenko, Eugene E. Kulikov, Vladimir A. Veselovsky, Maja V. Malakhova, Ivan A. Dyatlov, Elena N. Ilina, Egor A. Shitikov
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Microbiology
Subjects:
Klebsiella pneumoniae
multidrug-resistance
capsular type
capsule depolymerase
bacteriophage
Galleria mellonella
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.669618/full

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https://www.frontiersin.org/articles/10.3389/fmicb.2021.669618/full

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