Features and outcomes of patients admitted to the ICU for chimeric antigen receptor T cell-related toxicity: a French multicentre cohort

Features and outcomes of patients admitted to the ICU for chimeric antigen receptor T cell-related toxicity: a French multicentre cohort

Abstract Background Chimeric antigen receptor T-cell (CAR-T) therapy is increasingly used in patients with refractory haematological malignancies but can induce severe adverse events. We aimed to describe the clinical features and outcomes of patients admitted to the intensive care unit (ICU) after...

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Bibliographic Details
Main Authors: Corentin Le Cacheux, Audrey Couturier, Clara Sortais, Roch Houot, Morgane Péré, Thomas Gastinne, Amélie Seguin, Jean Reignier, Jean-Baptiste Lascarrou, Jean-Marc Tadié, Quentin Quelven, Emmanuel Canet
Format: Article
Language:English
Published: SpringerOpen 2024-01-01
Series:Annals of Intensive Care
Subjects:
Chimeric antigen receptor T Cell
Intensive care unit
Cytokine release syndrome
Immune effector cell-associated neurotoxicity syndrome
Haemophagocytic lymphohistiocytosis
Sepsis
Online Access:https://doi.org/10.1186/s13613-024-01247-9

Internet

https://doi.org/10.1186/s13613-024-01247-9

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