Disrupting enzyme fluidity
A combination of X-ray crystallography, NMR, and mass spectrometry has revealed how diverse small-molecule inhibitors bind Bruton’s tyrosine kinase and alter the conformation of this enzyme.
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Format: | Article |
Language: | English |
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eLife Sciences Publications Ltd
2021-01-01
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Series: | eLife |
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Online Access: | https://elifesciences.org/articles/65221 |