Comparative Analysis of the Physicochemical and Biological Characteristics of Freeze-Dried PEGylated Cationic Solid Lipid Nanoparticles

Comparative Analysis of the Physicochemical and Biological Characteristics of Freeze-Dried PEGylated Cationic Solid Lipid Nanoparticles

Cationic solid-lipid nanoparticles (cSLNs) have become a promising tool for gene and RNA therapies. PEGylation (PEG) is crucial in enhancing particle stability and protection. We evaluated the impact of PEG on the physicochemical and biological characteristics of cholesteryl-oleate cSLNs (CO-cSLNs)....

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Bibliographic Details
Main Authors: David A. Narváez-Narváez, María Duarte-Ruiz, Sandra Jiménez-Lozano, Cristina Moreno-Castro, Ronny Vargas, Anna Nardi-Ricart, Encarna García-Montoya, Pilar Pérez-Lozano, Josep Mª Suñé-Negre, Cristina Hernández-Munain, Carlos Suñé, Marc Suñé-Pou
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Pharmaceuticals
Subjects:
cationic solid lipid nanoparticles
cSLNs
poly(ethylene glycol)
PEG
freeze-drying
lyophilization
Online Access:https://www.mdpi.com/1424-8247/16/11/1583

Internet

https://www.mdpi.com/1424-8247/16/11/1583

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