Rapamycin modulates pulmonary pathology in a murine model of Mycobacterium tuberculosis infection

Rapamycin modulates pulmonary pathology in a murine model of Mycobacterium tuberculosis infection

Tuberculosis (TB) treatment regimens are lengthy, causing non-adherence to treatment. Inadequate treatment can lead to relapse and the development of drug resistance TB. Furthermore, patients often exhibit residual lung damage even after cure, increasing the risk for relapse and development of other...

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Bibliographic Details
Main Authors: Kamlesh Bhatt, Madhuri Bhagavathula, Sheetal Verma, Graham S. Timmins, Vojo P. Deretic, Jerrold J. Ellner, Padmini Salgame
Format: Article
Language:English
Published: The Company of Biologists 2021-10-01
Series:Disease Models & Mechanisms
Subjects:
tuberculosis
host-directed therapy
rapamycin
inflammation
Online Access:http://dmm.biologists.org/content/14/10/dmm049018

Internet

http://dmm.biologists.org/content/14/10/dmm049018

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