Transcriptional regulation of BMP2 expression by the PTH-CREB signaling pathway in osteoblasts.

Intermittent application of parathyroid hormone (PTH) has well established anabolic effects on bone mass in rodents and humans. Although transcriptional mechanisms responsible for these effects are not fully understood, it is recognized that transcriptional factor cAMP response element binding prote...

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Bibliographic Details
Main Authors: Rongrong Zhang, James R Edwards, Seon-Yle Ko, Shanshan Dong, Hongbin Liu, Babatunde O Oyajobi, Christopher Papasian, Hong-Wen Deng, Ming Zhao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3111437?pdf=render