The deleted in brachydactyly B domain of ROR2 is required for receptor activation by recruitment of Src.

The transmembrane receptor 'ROR2' resembles members of the receptor tyrosine kinase family of signalling receptors in sequence but its' signal transduction mechanisms remain enigmatic. This problem has particular importance because mutations in ROR2 are associated with two human skele...

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Bibliographic Details
Main Authors: Shiva Akbarzadeh, Lee M Wheldon, Steve M M Sweet, Sonia Talma, Faraz Khosravi Mardakheh, John K Heath
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2268744?pdf=render