TACE/ADAM17 substrates associate with ACS (Ep-CAM, HB-EGF) and follow-up MACE (TNFR1 and TNFR2)

TACE/ADAM17 substrates associate with ACS (Ep-CAM, HB-EGF) and follow-up MACE (TNFR1 and TNFR2)

Background and aims: TACE/ADAM17 is a membrane bound metalloprotease, which cleaves substrates involved in immune and inflammatory responses and plays a role in coronary artery disease (CAD). We measured TACE and its substrates in CAD patients to identify potential biomarkers within this molecular p...

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Bibliographic Details
Main Authors: Melody Chemaly, Roisin McAllister, Aaron Peace, Anthony John Bjourson, Steve Watterson, Andrew Parton, Matthias Clauss, Victoria McGilligan
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Atherosclerosis Plus
Subjects:
Coronary artery disease
Tumour necrosis factor alpha converting enzyme TACE/ADAM17
Major adverse cardiovascular events
Acute coronary syndrome
Online Access:http://www.sciencedirect.com/science/article/pii/S2667089522000505

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http://www.sciencedirect.com/science/article/pii/S2667089522000505

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