Oral supplementation of gut microbial metabolite indole-3-acetate alleviates diet-induced steatosis and inflammation in mice

Oral supplementation of gut microbial metabolite indole-3-acetate alleviates diet-induced steatosis and inflammation in mice

Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in Western countries. There is growing evidence that dysbiosis of the intestinal microbiota and disruption of microbiota-host interactions contribute to the pathology of NAFLD. We previously demonstrated that gut micr...

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Bibliographic Details
Main Authors: Yufang Ding, Karin Yanagi, Fang Yang, Evelyn Callaway, Clint Cheng, Martha E Hensel, Rani Menon, Robert C Alaniz, Kyongbum Lee, Arul Jayaraman
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-02-01
Series:eLife
Subjects:
liver
indole-3-acetic acid
microbiota
Online Access:https://elifesciences.org/articles/87458

Internet

https://elifesciences.org/articles/87458

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