Effects of <i>NR1I2</i> and <i>ABCB1</i> Genetic Polymorphisms on Everolimus Pharmacokinetics in Japanese Renal Transplant Patients

Effects of <i>NR1I2</i> and <i>ABCB1</i> Genetic Polymorphisms on Everolimus Pharmacokinetics in Japanese Renal Transplant Patients

The purpose of this study was to evaluate the effects of <i>NR1I2</i> (7635G>A and 8055C>T) and <i>ABCB1</i> (1236C>T, 2677G>T/A, and 3435C>T) genetic polymorphisms on everolimus pharmacokinetics in 98 Japanese renal transplant patients. On day 15 after everoli...

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Bibliographic Details
Main Authors: Hironobu Yagishita, Hideaki Kagaya, Mitsuru Saito, Kazuyuki Numakura, Ryohei Yamamoto, Ryuichiro Sagehashi, Tomonori Habuchi, Shigeru Satoh, Masatomo Miura
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:International Journal of Molecular Sciences
Subjects:
everolimus
polymorphism
pregnane X-receptor
P-glycoprotein
Online Access:https://www.mdpi.com/1422-0067/23/19/11742

Internet

https://www.mdpi.com/1422-0067/23/19/11742

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