Investigating the Role of 17-Beta Estradiol in the Regulation of the Unfolded Protein Response (UPR) in Pancreatic Beta Cells

Investigating the Role of 17-Beta Estradiol in the Regulation of the Unfolded Protein Response (UPR) in Pancreatic Beta Cells

Diabetes mellitus is clinically defined by chronic hyperglycemia. Sex differences in the presentation and outcome of diabetes exist with premenopausal women having a reduced risk of developing diabetes, relative to men, or women after menopause. Accumulating evidence shows a protective role of estro...

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Bibliographic Details
Main Authors: Monica De Paoli, Deep Shah, Alexander Zakharia, Zil Patel, Zinal Patel, Pakhi Pakhi, Geoff H. Werstuck
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:International Journal of Molecular Sciences
Subjects:
diabetes
17-beta estradiol
endoplasmic reticulum stress
unfolded protein response
pancreatic beta cells
Online Access:https://www.mdpi.com/1422-0067/25/3/1816

Internet

https://www.mdpi.com/1422-0067/25/3/1816

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