Variance component analysis of a multi-site study for the reproducibility of multiple reaction monitoring measurements of peptides in human plasma.

In the Addona et al. paper (Nature Biotechnology 2009), a large-scale multi-site study was performed to quantify Multiple Reaction Monitoring (MRM) measurements of proteins spiked in human plasma. The unlabeled signature peptides derived from the seven target proteins were measured at nine different...

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Bibliographic Details
Main Authors: Jessie Q Xia, Nell Sedransk, Xingdong Feng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3027641?pdf=render