Ferroptosis: A potential target for the intervention of intervertebral disc degeneration

Ferroptosis, an iron-dependent form of programmed cell death marked by phospholipid peroxidation, is regulated by complex cellular metabolic pathways including lipid metabolism, iron balance, redox homeostasis, and mitochondrial activity. Initial research regarding the mechanism of ferroptosis mainl...

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Bibliographic Details
Main Authors: Lu-Ping Zhou, Ren-Jie Zhang, Chong-Yu Jia, Liang Kang, Zhi-Gang Zhang, Hua-Qing Zhang, Jia-Qi Wang, Bo Zhang, Cai-Liang Shen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.1042060/full