Naringin alleviates pneumonia caused by Klebsiella pneumoniae infection by suppressing NLRP3 inflammasome

Naringin alleviates pneumonia caused by Klebsiella pneumoniae infection by suppressing NLRP3 inflammasome

Klebsiella pneumoniae (Kpn) is an important pathogen of hospital-acquired pneumonia, which can lead to sepsis and death in severe cases. In this study, we simulated pneumonia induced by Kpn infection in mice to investigate the therapeutic effect of naringin (NAR) on bacterial-induced lung inflammati...

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Bibliographic Details
Main Authors: Xiao-Han Jing, Guan-Yu Zhao, Gui-Bo Wang, Qi-Lin Huang, Wen-Shu Zou, Li-Na Huang, Wei Li, Zheng-Ying Qiu, Rui-Hua Xin
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Klebsiella pneumoniae
NLRP3 inflammasome
Naringin
Anti-inflammatory mechanism
Protein assembly
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223018267

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http://www.sciencedirect.com/science/article/pii/S0753332223018267

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