An investigation of plasma cell-free RNA for the detection of colorectal cancer: From transcriptome marker selection to targeted validation.

Regular screening for colorectal cancer (CRC) is critical for early detection and long-term survival. Despite the current screening options available and advancements in therapies there will be around 53,000 CRC related deaths this year. There is great interest in non-invasive alternatives such as p...

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Main Authors: Emmalee J Northrop-Albrecht, Chung Wah Wu, Calise K Berger, William R Taylor, Patrick H Foote, Karen A Doering, Anna M Gonser, Aditya Bhagwate, Zhifu Sun, Douglas W Mahoney, Kelli N Burger, Lisa A Boardman, John B Kisiel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0308711