Platelet-Derived Microparticles From Obese Individuals: Characterization of Number, Size, Proteomics, and Crosstalk With Cancer and Endothelial Cells

Platelet-Derived Microparticles From Obese Individuals: Characterization of Number, Size, Proteomics, and Crosstalk With Cancer and Endothelial Cells

Rationale: Obesity is a risk factor for atherothrombosis and various cancers. However, the mechanisms are not yet completely clarified.Objectives: We aimed to verify whether the microparticles (MPs) released from thrombin-activated platelets differed in obese and non-obese women for number, size, an...

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Bibliographic Details
Main Authors: Rosalia Grande, Melania Dovizio, Simone Marcone, Paulina B. Szklanna, Annalisa Bruno, H. Alexander Ebhardt, Hilary Cassidy, Fionnuala Ní Áinle, Anna Caprodossi, Paola Lanuti, Marco Marchisio, Geltrude Mingrone, Patricia B. Maguire, Paola Patrignani
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Pharmacology
Subjects:
microparticles
platelets
obesity
proteomics
cellular cross-talk
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00007/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.00007/full

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