HLA-A*03, the hemochromatosis ancestral haplotype, and phenotypes of referred hemochromatosis probands with HFE p.C282Y homozygosity

HLA-A*03, the hemochromatosis ancestral haplotype, and phenotypes of referred hemochromatosis probands with HFE p.C282Y homozygosity

Abstract Background Human leukocyte antigen (HLA)-A*03, hemochromatosis ancestral haplotype marker, was associated with greater iron overload in hemochromatosis cohorts reported before discovery of the HFE gene. We sought to learn whether an A*03-linked locus influences phenotypes in referred HFE p....

Full description

Bibliographic Details
Main Authors: James C. Barton, J. Clayborn Barton, Ronald T. Acton
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Hereditas
Subjects:
Ancestral haplotype
APRI
FIB-4
Haplotype
Iron overload
Online Access:https://doi.org/10.1186/s41065-022-00237-w

Internet

https://doi.org/10.1186/s41065-022-00237-w

Similar Items