5'HS5 of the human beta-globin locus control region is dispensable for the formation of the beta-globin active chromatin hub.

5'HS5 of the human beta-globin locus control region is dispensable for the formation of the beta-globin active chromatin hub.

Hypersensitive site 5 (5'HS5) of the beta-globin Locus Control Region functions as a developmental stage-specific border in erythroid cells. Here, we have analyzed the role of 5'HS5 in the three dimensional organization of the beta-gene locus using the Chromatin Conformation Capture (3C) t...

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Bibliographic Details
Main Authors: Ping Kei Chan, Albert Wai, Sjaak Philipsen, Kian-Cheng Tan-Un
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2358975?pdf=render

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http://europepmc.org/articles/PMC2358975?pdf=render

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