Sulfadiazine Exerts Potential Anticancer Effect in HepG2 and MCF7 Cells by Inhibiting TNFα, IL1b, COX-1, COX-2, 5-LOX Gene Expression: Evidence from In Vitro and Computational Studies

Sulfadiazine Exerts Potential Anticancer Effect in HepG2 and MCF7 Cells by Inhibiting TNFα, IL1b, COX-1, COX-2, 5-LOX Gene Expression: Evidence from In Vitro and Computational Studies

Drug repurposing is a promising approach that has the potential to revolutionize the drug discovery and development process. By leveraging existing drugs, we can bring new treatments to patients more quickly and affordably. Anti-inflammatory drugs have been shown to target multiple pathways involved...

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Bibliographic Details
Main Authors: Mohamed Gomaa, Wael Gad, Dania Hussein, Faheem Hyder Pottoo, Nada Tawfeeq, Mansour Alturki, Dhay Alfahad, Razan Alanazi, Ismail Salama, Mostafa Aziz, Aboelnasr Zahra, Abeer Hanafy
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Pharmaceuticals
Subjects:
sulfadiazine
anti-inflammatory
anticancer
TNFα
IL1b
COX-1
Online Access:https://www.mdpi.com/1424-8247/17/2/189

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https://www.mdpi.com/1424-8247/17/2/189

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