Constructing gene regulatory networks using epigenetic data

Abstract The biological processes that drive cellular function can be represented by a complex network of interactions between regulators (transcription factors) and their targets (genes). A cell’s epigenetic state plays an important role in mediating these interactions, primarily by influencing chr...

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Bibliographic Details
Main Authors: Abhijeet Rajendra Sonawane, Dawn L. DeMeo, John Quackenbush, Kimberly Glass
Format: Article
Language:English
Published: Nature Portfolio 2021-12-01
Series:npj Systems Biology and Applications
Online Access:https://doi.org/10.1038/s41540-021-00208-3