Foxp3 represses retroviral transcription by targeting both NF-kappaB and CREB pathways.

Foxp3 represses retroviral transcription by targeting both NF-kappaB and CREB pathways.

Forkhead box (Fox)/winged-helix transcription factors regulate multiple aspects of immune responsiveness and Foxp3 is recognized as an essential functional marker of regulatory T cells. Herein we describe downstream signaling pathways targeted by Foxp3 that may negatively impact retroviral pathogene...

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Bibliographic Details
Main Authors: Christian Grant, Unsong Oh, Kazunori Fugo, Norihiro Takenouchi, Caitlin Griffith, Karen Yao, Timothy E Newhook, Lee Ratner, Steven Jacobson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-04-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC1447668?pdf=render

Internet

http://europepmc.org/articles/PMC1447668?pdf=render

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