A combined screening platform for HIV treatment failure and resistance.

To develop a low cost method to screen for virologic failure of antiretroviral therapy (ART) and HIV-1 drug resistance, we performed a retrospective evaluation of a screening assay using serial dilutions of HIV-1 RNA-spiked blood plasma and samples from patients receiving >6 months of first-line...

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Bibliographic Details
Main Authors: Myres W Tilghman, Susanne May, Josué Pérez-Santiago, Caroline C Ignacio, Susan J Little, Douglas D Richman, Davey M Smith
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3338506?pdf=render