Rapid, Reference-Free human genotype imputation with denoising autoencoders
Genotype imputation is a foundational tool for population genetics. Standard statistical imputation approaches rely on the co-location of large whole-genome sequencing-based reference panels, powerful computing environments, and potentially sensitive genetic study data. This results in computational...
Main Authors: | Raquel Dias, Doug Evans, Shang-Fu Chen, Kai-Yu Chen, Salvatore Loguercio, Leslie Chan, Ali Torkamani |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2022-09-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/75600 |
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