Lipid metabolism, oxidative stress and cell death are regulated by PKC delta in a dietary model of nonalcoholic steatohepatitis.

Lipid metabolism, oxidative stress and cell death are regulated by PKC delta in a dietary model of nonalcoholic steatohepatitis.

Steatosis, oxidative stress, and apoptosis underlie the development of nonalcoholic steatohepatitis (NASH). Protein kinase C delta (PKCδ) has been implicated in fatty liver disease and is activated in the methionine and choline-deficient (MCD) diet model of NASH, yet its pathophysiological importanc...

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Bibliographic Details
Main Authors: Michael W Greene, Christine M Burrington, Darin T Lynch, Samantha K Davenport, Andrew K Johnson, Melissa J Horsman, Saleem Chowdhry, Jian Zhang, Janet D Sparks, Paul C Tirrell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3893275?pdf=render

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http://europepmc.org/articles/PMC3893275?pdf=render

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