Heterogeneity of tumor immune microenvironment and real-world analysis of immunotherapy efficacy in lung adenosquamous carcinoma

Heterogeneity of tumor immune microenvironment and real-world analysis of immunotherapy efficacy in lung adenosquamous carcinoma

Lung adenosquamous carcinoma (ASC) is an uncommon histological subtype. We aimed to characterize the tumor immune microenvironment (TIME) in lung ASC and estimate patient response to immune checkpoint inhibitors (ICIs), which have never been systematically investigated. In cohort I, we collected 30...

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Bibliographic Details
Main Authors: Chao Li, Xiaobin Zheng, Pansong Li, Huijuan Wang, Jie Hu, Lin Wu, Zhijie Wang, Hui Guo, Fang Wu, Wenzhao Zhong, Chengzhi Zhou, Qian Chu, Jun Zhao, Xinlong Zheng, Weijin Xiao, Weifeng Zhu, Longfeng Zhang, Qian Li, Kan Jiang, Qian Miao, Biao Wu, Yiquan Xu, Shiwen Wu, Haibo Wang, Shanshan Yang, Yujing Li, Xuefeng Xia, Xin Yi, Cheng Huang, Bo Zhu, Gen Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Immunology
Subjects:
lung adenosquamous carcinoma
tumor immune microenvironment
heterogeneity
PD-L1 expression
immune checkpoint inhibitor
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.944812/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.944812/full

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