Intersectin-1s deficiency in pulmonary pathogenesis

Intersectin-1s deficiency in pulmonary pathogenesis

Abstract Intersectin-1s (ITSN-1s), a multidomain adaptor protein, plays a vital role in endocytosis, cytoskeleton rearrangement and cell signaling. Recent studies have demonstrated that deficiency of ITSN-1s is a crucial early event in pulmonary pathogenesis. In lung cancer, ITSN-1s deficiency impai...

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Bibliographic Details
Main Authors: Niranjan Jeganathan, Dan Predescu, Sanda Predescu
Format: Article
Language:English
Published: BMC 2017-09-01
Series:Respiratory Research
Subjects:
Intersectin-1s
Pulmonary arterial hypertension
Lung cancer
Acute lung injury
Eps8
mSos1
Online Access:http://link.springer.com/article/10.1186/s12931-017-0652-4

Internet

http://link.springer.com/article/10.1186/s12931-017-0652-4

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