Perilla frutescens Extracts Protects against Dextran Sulfate Sodium-Induced Murine Colitis: NF-κB, STAT3, and Nrf2 as Putative Targets

Perilla frutescens Extracts Protects against Dextran Sulfate Sodium-Induced Murine Colitis: NF-κB, STAT3, and Nrf2 as Putative Targets

Perilla frutescens is a culinary and medicinal herb which has a strong anti-inflammatory and antioxidative effects. In the present study, we investigated the effects of Perilla frutescens extract (PE) against dextran sulfate sodium (DSS)-induced mouse colitis, an animal model that mimics human infla...

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Bibliographic Details
Main Authors:	Deung Dae Park, Hye-Won Yum, Xiancai Zhong, Seung Hyeon Kim, Seong Hoon Kim, Do-Hee Kim, Su-Jung Kim, Hye-Kyung Na, Atsuya Sato, Takehito Miura, Young-Joon Surh
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2017-08-01
Series:	Frontiers in Pharmacology
Subjects:	colitis dextran sulfate sodium inflammatory bowel disease Perilla frutescens NF-κB STAT3
Online Access:	http://journal.frontiersin.org/article/10.3389/fphar.2017.00482/full

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