Loss of Brain Angiogenesis Inhibitor-3 (BAI3) G-Protein Coupled Receptor in Mice Regulates Adaptive Thermogenesis by Enhancing Energy Expenditure

Loss of Brain Angiogenesis Inhibitor-3 (BAI3) G-Protein Coupled Receptor in Mice Regulates Adaptive Thermogenesis by Enhancing Energy Expenditure

Effective energy expenditure is critical for maintaining body weight (BW). However, underlying mechanisms contributing to increased BW remain unknown. We characterized the role of brain angiogenesis inhibitor-3 (BAI3/ADGRB3), an adhesion G-protein coupled receptor (aGPCR), in regulating BW. A CRISPR...

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Bibliographic Details
Main Authors: Haifa Alsharif, Mary N. Latimer, Katherine C. Perez, Justin Alexander, Md Mostafizur Rahman, Anil K. Challa, Jeong-A. Kim, Sasanka Ramanadham, Martin Young, Sushant Bhatnagar
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Metabolites
Subjects:
BAI3
GPCR
energy expenditure
adaptive thermogenesis
body weight
brown adipose tissue
Online Access:https://www.mdpi.com/2218-1989/13/6/711

Internet

https://www.mdpi.com/2218-1989/13/6/711

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